Connecting urolithin A, which is formed in the intestine after the consumption of pomegranates and raspberries, has successfully passed the first clinical trials on humans. Swiss researchers conducted an experiment, hopefully as soon as possible to release a new anti-aging drug on the market. It stimulates the mitochondria and is able to reverse age-related muscle loss.
Researchers from the Federal Polytechnic school of Lausanne successfully tested on humans a new anti-aging agent connection called urolithin And extracted from the fruit pomegranate. In previous experiments using this molecule has already allowed significantly extend the life of worms and mice by stimulating the work of the mitochondria.
According to the New Atlas, the first phase of clinical trials of elderly and relatively healthy volunteers received a single dose urolithin A weight of from 250 to 2000 mg. a Comparison with the control group revealed no adverse effects and safety risks.
Then, 60 participants were divided into 4 subgroups to study long-term effects of the compound. Within 28 days of each subgroup received daily either placebo or one dose of urolithin And is 250 mg, 500 mg or 1000 mg.
During the tests it was found that doses of 500 mg and 1000 mg improve the functioning of mitochondria in skeletal muscle, that is, have an effect similar to exercise. Scientists hope this will allow you to use urolithin And to slow down and even reverse age-related muscle loss.
The team plans to continue research of promising compounds and to create on its basis a commercial drug.
One of the effective ways to slow down aging and reduce the risk of age-related diseases — changing your diet. For example, avoiding red meat in favor of fish and nuts can significantly reduce the risk of death, scientists say.