Platelet-Rich Plasma Injections therapy, or PRP, was invented in 1987. The idea was based on older concepts of autohematherapy i.e. using patient’s own blood to treat the specific conditions. Unlike the basic therapy Platelet-Rich Plasma has rich evidence body and can be applied topically, exactly where the disease made a nest. It is widely used in treatment of sport trauma, chronic sport trauma and osteoarthritis. PRP may show positive effects in some cosmetic procedures too.
One of the Platelet-Rich Plasma Injections therapy is simplicity yet great effect. In general the procedures have several stages and the most important is centrifuging the patient’s blood to separate the platelet-reach faction and prepare the infusion.
The most common way to prepare PRP involves putting a patient’s blood in a centrifuge. A proper tube, like the ones listed under the link, is subsequently placed in an appratus, where it is separated into layers. There are such layers:
Erythrocytes, the red blood cells, constitute approximately 45% of blood, are forced to accumulate at the bottom of the tube and discarded
Leikocytes and thrombocytes (platelets) are concentrated in a middle layer. They comprise less than 1 percent of the initial blood sample.
Plasma with a low cellular content forms the upper layer layer. It is majority of content. About 55 percent of the sample is plasma.
After the centrifuging is done medical personnel prepares the proper PRP solution. It is usually done by high-skilled lab workers. It is important to know, that different spinning parameters are needed to achieve the proper preparation. The speed and duration of the separation process is essential and depends on the exact nature of the therapy, the diagnosis and generally is dictated by the doctor. Osteoarthritis, for example, is one of the disease with no proven parameters of the centrifuging. Each doctor acts upon his own experience.
Working PRP solution is made from a patients’s own blood thus eliminating the need for immunologic connectivity and strict control of donors. It is blood enriched in thrombocites, also known as platelets. Their presence and cycling through the system is critical for regeneration and blood clotting. Thrombocites and the plasma faction of the blood contain substances essential for the cell growth and regeneration. It is exactly what is required for the therapy of trauma and degenerative diseases.