In Brazil failed trials of anti-malarial drug: died on 11 volunteers

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The tests were performed on 81 patients.

Brazilian scientists stopped testing anti-malarial drug chloroquine, which treat patients with coronavirus Ukrainians, due to the death of 11 participants in the experiment. It is the eighth part of all who experienced the drug, reports the Chronicle.info with reference to Country.

The test involved 81 the patient, who was hospitalized with SARS in Manaus (in the Brazilian state of Amazonas).

During the experiment, study participants were divided into two groups: the first (41) was to receive a dose of 600 mg of chloroquine twice a day for 10 days, the second (40) — 450 mg twice on the first day, and then once in five days.

Patients in the study were also given the antibiotic azithromycin, which also gives the load on the heart.

Within three days, the researchers began to notice heart arrhythmia in patients who take higher dose. Before the sixth day of treatment died on 11 patients, which resulted in the immediate completion phase of the study with high doses.

Preliminary results showed that the administration of large doses of chloroquine for 10 days can be recommended in the treatment of Covid-19 because of the risk of violations of normal (sinus) heart rhythm characterized by rapid contraction of the ventricles.

We will remind that the President of the United States trump enthusiastically promoted drugs with chloroquine as a potential treatment for a new coronavirus, despite the small amount of evidence that they work, and despite the concerns of some senior officials of health.

Earlier in Sweden refused to use the antimalarial drug chloroquine for the treatment of coronavirus, which causes serious side effects in the form of spasms and migraines, and can lead to loss of vision.

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